circRNA basic information
circBase ID: hsa_circ_0001495
Name: hsa_circ_CCNB1
Synonym: -
Host Gene: hsa-miR-527
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human BCa cell lines (RT4, J82, 5637, T24, UM-UC-3, HT-1376, TCCSUP), human normal urothelial cell lines (SV-HUC-1, HEK293T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Robo1
Associated microRNA: hsa-miR-527
Biological function: circ_0001495 was found to promote the proliferation, migration and invasion of BCa cells in vitro
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_0001495 was found to promote the proliferation, migration and invasion of BCa cells in vitro through the miR-527/Robo1 axis and promote the growth and metastasis of BCa tumors in vivo.
Other information
Title:

Circular RNA_0001495 increases Robo1 expression by sponging microRNA-527 to promote the proliferation, migration and invasion of bladder cancer cells.

Journal: Carcinogenesis
Published: 2021/5/23
PubMed ID: 34021307