circRNA basic information
circBase ID: -
Name: hsa_circ_VPS33B
Synonym: circVPS33B
Host Gene: hsa-miR-873-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Infiltrative GC cells XGC-1. human gastric epithelial mucosa cells (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HNRNPK
Associated microRNA: hsa-miR-873-5p
Biological function: CircVPS33B silencing decreased tumor growth in vivo and inhibited proliferation, migration, invasion, EMT, and Warburg effect of infiltrative GC cells in vitro
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

CircVPS33B accelerated Warburg effect and tumor growth through regulating the miR-873-5p/HNRNPK axis in infiltrative GC, manifesting that circVPS33B might be a potential target for infiltrative GC treatment.
Other information
Title:

Inhibition of circRNA circVPS33B Reduces Warburg Effect and Tumor Growth Through Regulating the miR-873-5p/HNRNPK Axis in Infiltrative Gastric Cancer.

Journal: Onco Targets Ther
Published: 2021/5/21
PubMed ID: 34012268