circRNA basic information
circBase ID: hsa_circ_0080223
Name: hsa_circ_EGFR
Synonym: circ-EGFR
Host Gene: hsa-miR-183-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human glioma cell lines (LN229, T98G)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TUSC2
Associated microRNA: hsa-miR-183-5p
Biological function: circ-EGFR overexpression induced the repression of cell proliferation, migration, and invasion but the promotion of apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

circ-EGFR inhibited the malignant progression of glioma by regulating the levels of miR-183-5p and TUSC2.
Other information
Title:

Circ-EGFR Functions as an Inhibitory Factor in the Malignant Progression of Glioma by Regulating the miR-183-5p/TUSC2 Axis.

Journal: Cell Mol Neurobiol
Published: 2021/5/17
PubMed ID: 33993369