circRNA basic information
circBase ID: -
Name: hsa_circ_Ube2k
Synonym: circUbe2k
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 409
DO name: liver disease
Disease details: hepatic fibrosis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGF-beta2
Associated microRNA: hsa-miR-149-5p
Biological function: inhibiting circUbe2k expression reduced hepatic stellate cells (HSCs) activation and proliferation
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circUbe2k may act as a catalyst of HSCs activation and HF through the circUbe2k/miR-149-5p/TGF-beta2 axis.
Other information
Title:

Circular RNA circUbe2k promotes hepatic fibrosis via sponging miR-149-5p/TGF-beta2 axis.

Journal: FASEB J
Published: 2021/5/14
PubMed ID: 33982351