circRNA basic information
circBase ID: -
Name: hsa_circ_BFAR
Synonym: circBFAR
Host Gene: hsa-miR-513a-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human GC cell lines (BGC-823, MKN-28, MGC-803, SGC7901, HGC-27, AGS), gastric epithelial cell line (GES-1), human embryonic kidney cell line (HEK-293T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HK2
Associated microRNA: hsa-miR-513a-3p
Biological function: circBFAR was proven to promote GC proliferation
Molecular mechanism: by targeting the hsa-miR-513a-3p/hexokinase 2 (HK2) axis
Survival: -
Supported No.:
 1
Description:

we found a circBFAR/miR-513a-3p/HK2 axis in GC and revealed the relationship between circBFAR and glycolysis for the first time. circBFAR may serve as a novel target of GC individualized therapy.
Other information
Title:

Knockdown of circBFAR inhibits proliferation and glycolysis in gastric cancer by sponging miR-513a-3p/hexokinase 2 axis.

Journal: Biochem Biophys Res Commun
Published: 2021/5/13
PubMed ID: 33979737