circRNA basic information
circBase ID: -
Name: -
Synonym: CircRNA_30032
Host Gene: mmu-miR-96-5p
 
 
 
Disease basic information
DO ID:
0050855
DO name: renal fibrosis
Disease details: renal fibrosis
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HBEGF/KRAS
Associated microRNA: mmu-miR-96-5p
Biological function: -
Molecular mechanism: sponging mmu-miR-96-5p and increasing the expression of profibrotic proteins, including HBEGF, KRAS, collagen I, collagen III and fibronectin
Survival: -
Supported No.:
1
Description:

circRNA_30032 promotes renal fibrosis via the miR-96-5p/HBEGF/KRAS axis and suggest that circRNA_30032 is a potential therapeutic target for treatment of renal fibrosis.

Other information
Title:

CircRNA_30032 promotes renal fibrosis in UUO model mice via miRNA-96-5p/HBEGF/KRAS axis.

Journal: Aging (Albany NY)
Published: 2021/5/12
PubMed ID: 33973871