circRNA basic information
circBase ID: -
Name: hsa_circ_CACNG2
Synonym: circ-CACNG2
Host Gene: hsa-miR-197-3p
 
 
 
Disease basic information
DO ID:
9538
DO name: multiple myeloma
Disease details: multiple myeloma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: H9C2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: caspase3
Associated microRNA: hsa-miR-197-3p
Biological function: cardiomyocyte viability and apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

MM-exosomes could inhibit cardiomyocyte viability and promote apoptosis partially through circ-CACNG2/miR-197-3p/caspase3 axis.

Other information
Title:

Exosomal circ-CACNG2 promotes cardiomyocyte apoptosis in multiple myeloma via modulating miR-197-3p/caspase3 axis.

Journal: Exp Cell Res
Published: 2022/6/2
PubMed ID: 35649477