circRNA basic information
circBase ID: hsa_circ_0069094
Name: hsa_circ_S100P
Synonym: -
Host Gene: hsa-miR-661
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MCF-10A cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA1
Associated microRNA: hsa-miR-661
Biological function: hsa_circ_0069094 knockdown inhibited cell glycolysis, proliferation, migration and invasion, whereas induced cell apoptosis in breast cancer
Molecular mechanism: hsa_circ_0069094 regulated HMGA1 by sponging hsa-miR-661
Survival: -
Supported No.:
 4
Description:

hsa_circ_0069094 knockdown repressed breast cancer cell carcinogenesis and cell glycolysis by regulating HMGA1 through sponging miR-661, which provided a new insight for studying the mechanism of hsa_circ_0069094 in modulating breast cancer development.
Other information
Title:

Hsa_circ_0069094 knockdown inhibits cell proliferation, migration, invasion and glycolysis, while induces cell apoptosis by miR-661/HMGA1 axis in breast cancer.

Journal: Anticancer Drugs
Published: 2021/5/1
PubMed ID: 33929992