circRNA basic information
circBase ID: -
Name: hsa_circ_SEPT9
Synonym: CircSEPT9
Host Gene: hsa-miR-432-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: glioma cell lines (A172, T98G, LN229, LN18, LN382, CAS1, DBTRG), human normal astrocyte line (NHA)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LASP1
Associated microRNA: hsa-miR-432-5p
Biological function: CircSEPT9 interference inhibited the proliferation, migration, invasion and glycolytic metabolism and triggered the apoptosis of glioma cells
Molecular mechanism: binding to hsa-miR-432-5p to induce LASP1 expression
Survival: -
Supported No.:
 1
Description:

CircSEPT9 exerted an oncogenic role to enhance the malignant behaviors of glioma cells by binding to miR-432-5p to induce LASP1 expression.
Other information
Title:

CircRNA SEPT9 contributes to malignant behaviors of glioma cells via miR-432-5p-mediated regulation of LASP1.

Journal: Brain Res
Published: 2021/4/30
PubMed ID: 33915163