circRNA basic information
circBase ID: hsa_circ_0072309
Name: hsa_circ_LIFR
Synonym: -
Host Gene: hsa-miR-607
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human bronchial epithelial cells (HBE), human NSCLC cells (H1975, H1650)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: FTO
Associated microRNA: hsa-miR-607
Biological function: hsa_circ_0072309 promotes the proliferation, migration, and invasion
Molecular mechanism: hsa_circ_0072309 interacted with hsa-miR-607 via its miRNA response element to upregulate the expression of FTO
Survival: -
Supported No.:
 3
Description:

hsa_circ_0072309 promotes the proliferation, migration, and invasion of NSCLC cells. In vitro precipitation of circRNAs, luciferase reporter assays, and biotin-coupled microRNA capture assays were carried out to investigate the mechanisms by which hsa_circ_0072309 regulates NSCLC.

Other information
Title:

Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma.

Journal: Aging (Albany NY)
Published: 2021/4/22
PubMed ID: 33879631