circRNA basic information
circBase ID: -
Name: hsa_circ_ATP5B
Synonym: -
Host Gene: hsa-miR-185-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HOXB5
Associated microRNA: hsa-miR-185-5p
Biological function: circATP5B expression was significantly upregulated in GSCs and promoted the proliferation of GSCs
Molecular mechanism: acted as hsa-miR-185-5p sponge to upregulate HOXB5 expression
Survival: -
Supported No.:
 1
Description:

Our study identified the SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop in GSCs. This provides an effective biomarker for glioma diagnosis and prognostic evaluation.
Other information
Title:

The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway.

Journal: J Exp Clin Cancer Res
Published: 2021/4/17
PubMed ID: 33858489