circRNA basic information
circBase ID: hsa_circ_0004872
Name: hsa_circ_MAPK1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BGC-823, SGC-7901, MGC-803, MKN-45, HGC-27, AGS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: MAPK signaling
Associated microRNA: -
Biological function: CircMAPK1 inhibited the proliferation and invasion of gastric cancer cells in vitro and in vivo
Molecular mechanism: -
Survival: better
Supported No.:
 2
Description:

Our study revealed that circMAPK1 inhibits the malignant biological behavior of gastric cancer cells through its encoded protein MAPK1-109aa. More importantly, circMAPK1 is a favorable predictor for gastric cancer patients and may provide a new therapeutic target in the treatment of gastric cancer.
Other information
Title:

A novel protein encoded by circMAPK1 inhibits progression of gastric cancer by suppressing activation of MAPK signaling.

Journal: Mol Cancer
Published: 2021/4/11
PubMed ID: 33836754