circRNA basic information
circBase ID: hsa_circ_0094342
Name: hsa_circ_PTEN
Synonym: -
Host Gene: hsa-miR-155, hsa-miR-330-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A549, HCC827
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-155, hsa-miR-330-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: better
Supported No.:
 1
Description:

circ-PTEN functions as a tumor-inhibiting circRNA in NSCLC through post-transcriptionally regulating PTEN, hinting a promising diagnostic/prognostic biomarker as well as therapeutic target for NSCLC patients.
Other information
Title:

Circular RNA circ-PTEN elevates PTEN inhibiting the proliferation of non-small cell lung cancer cells.

Journal: Hum Cell
Published: 2021/4/7
PubMed ID: 33821441