circRNA basic information
circBase ID: hsa_circ_0091579
Name: -
Synonym: Circ_0091579
Host Gene: hsa-miR-1287
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HB611, Huh-7, MHCC97, SNU423
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PDK2
Associated microRNA: hsa-miR-1287
Biological function: Circ_0091579 mediated the promotion of proliferation and glycolysis and the suppression of apoptosis of HCC cells
Molecular mechanism: Circ_0091579 upregulated the enrichment of PDK2 by acting as a sponge of hsa-miR-1287 in HCC cells
Survival: -
Supported No.:
 6
Description:

Circ_0091579 deteriorated HCC by promoting the proliferation and glycolytic metabolism and suppressing the apoptosis of HCC cells via miR-1287/PDK2 axis.
Other information
Title:

Circ_0091579 enhances the malignancy of hepatocellular carcinoma via miR-1287/PDK2 axis.

Journal: Open Life Sci
Published: 2021/4/6
PubMed ID: 33817300