circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-381-3p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: H1975, A549 , H1299
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AKT, mTOR
Associated microRNA: hsa-miR-381-3p
Biological function: promote proliferation, migration, and glycolysis
Molecular mechanism: activating the AKT/mTOR signaling pathway
Survival: -
Supported No.:
 4
Description:

circHIPK3 knockdown suppressed tumor growth in vivo by inactivating the AKT/mTOR signaling pathway.
Other information
Title:

CircHIPK3/miR-381-3p axis modulates proliferation, migration, and glycolysis of lung cancer cells by regulating the AKT/mTOR signaling pathway.

Journal: Open Life Sci
Published: 2021/4/6
PubMed ID: 33817257