circRNA basic information
circBase ID: hsa_circ_0071589
Name: -
Synonym: circ_0071589
Host Gene: hsa-miR-526b-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HCT116, LOVO
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF12
Associated microRNA: hsa-miR-526b-3p
Biological function: Circ_0071589 knockdown inhibited CDDP resistance, proliferation, migration and invasion, and promoted apoptosis in CDDP-resistant CRC cells
Molecular mechanism: Circ_0071589 regulated KLF12 expression through modulating hsa-miR-526b-3p
Survival: -
Supported No.:
 2
Description:

Knockdown of circ_0071589 repressed CDDP resistance in CDDP-resistant CRC cells by regulating the miR-526b-3p/KLF12 axis.
Other information
Title:

Downregulation of Circ_0071589 Suppresses Cisplatin Resistance in Colorectal Cancer by Regulating the MiR-526b-3p/KLF12 Axis.

Journal: Cancer Manag Res
Published: 2021/4/2
PubMed ID: 33790646