circRNA basic information
circBase ID: hsa_circ_0000629
Name: -
Synonym: circ_0000629
Host Gene: hsa-miR-1290
 
 
 
Disease basic information
DO ID:
11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: 5637, J82, T24, SW780
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CDC73
Associated microRNA: hsa-miR-1290
Biological function: circ_0000629 significantly inhibited the development and metastasis of BC cells
Molecular mechanism: Circ_0000629 localized in the cytoplasm and regulated CDC73 expression by sponging hsa-miR-1290
Survival: -
Supported No.:
1
Description:

Circ_0000629 promotes the expression of CDC73 by competitively binding to miR-1290, thereby inhibiting the growth and metastasis of BC cells.

Other information
Title:

Circular RNA_0000629 Suppresses Bladder Cancer Progression Mediating MicroRNA-1290/CDC73.

Journal: Cancer Manag Res
Published: 2021/4/2
PubMed ID: 33790645