circRNA basic information
circBase ID: -
Name: hsa_circ_SOBP
Synonym: -
Host Gene: hsa-miR-141-3p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HEK293T, RWPE_1, DU145, PC_3, LNCap, 22Rv1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MYPT1/p-MLC2
Associated microRNA: hsa-miR-141-3p
Biological function: CircSOBP depletion increased migration and invasion and induced amoeboid migration of PCa cells.
Molecular mechanism: circSOBP bound hsa-miR-141-3p and regulated the MYPT1/p-MLC2 axis
Survival: -
Supported No.:
 1
Description:

circSOBP suppresses amoeboid migration of PCa cells and inhibits migration and invasion through sponging miR-141-3p and regulating the MYPT1/p-MLC2 axis.
Other information
Title:

Novel circular RNA circSOBP governs amoeboid migration through the regulation of the miR-141-3p/MYPT1/p-MLC2 axis in prostate cancer.

Journal: Clin Transl Med
Published: 2021/3/31
PubMed ID: 33784000