circRNA basic information
circBase ID: -
Name: hsa_circ_EXOC7
Synonym: -
Host Gene: hsa-miR-149-3p
 
 
 
Disease basic information
DO ID:
 4451
DO name: renal carcinoma
Disease details: renal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW839, 786_O, Caki_1, ACHN, HEK293T
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CSF1
Associated microRNA: hsa-miR-149-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

AR/DHX9/circEXOC7/miR-149-3p/CSF1 signaling acts as a valuable feature in the bone metastasis of renal cancer, which may benefit in suppressing the RBM progression.
Other information
Title:

Androgen receptor decreases renal cell carcinoma bone metastases via suppressing the osteolytic formation through altering a novel circEXOC7 regulatory axis.

Journal: Clin Transl Med
Published: 2021/3/31
PubMed ID: 33783995