circRNA basic information
circBase ID: hsa_circ_0005397
Name: hsa_circ_RHOT1
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCCLM3, Huh7
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PDK2
Associated microRNA: hsa-miR-326
Biological function: Hsa_circ_0005397 knockdown inhibited cell proliferation and metastasis, and promoted apoptosis.
Molecular mechanism: hsa-miR-326/PDK2 axis
Survival: -
Supported No.:
 3
Description:

Hsa_circ_0005397 facilitates HCC progression by regulating the miR-326/PDK2 axis, providing a promising circRNA-targeted therapy for HCC.
Other information
Title:

Circular RNA hsa_circ_0005397 promotes hepatocellular carcinoma progression by regulating the miR-326/PDK2 axis.

Journal: J Gene Med
Published: 2021/3/31
PubMed ID: 33783904