circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-222-3p
 
 
 
Disease basic information
DO ID:
 319
DO name: spinal cord disease
Disease details: spinal cord injury
Species: human
Species details: human
Sample type: cell line
Sample type details: AGE1.HN
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: DUSP19
Associated microRNA: hsa-miR-222-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

The regulation of circ_HIPK3 in CoCl(2)-induced injury of AGE1.HN cells was associated with the upregulation of DUSP19. Circ_HIPK3 acted as a pathogenic inhibitor in the progression of SCI via the miR-222-3p-mediated DUSP19 upregulation.
Other information
Title:

Circ_HIPK3 alleviates CoCl(2)-induced apoptotic injury in neuronal cells by depending on the regulation of the miR-222-3p/DUSP19 axis.

Journal: Biochem Biophys Res Commun
Published: 2021/3/27
PubMed ID: 33770577