circRNA basic information
circBase ID: hsa_circ_0000567
Name: hsa_circ_SETD3
Synonym: -
Host Gene: hsa-miR-520h
 
 
 
Disease basic information
DO ID:
1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-520h
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

circSETD3 can be used as a novel biomarker for lung cancer. It relieves miR-520h degradation of the transporter ABCG2 by down-regulating the miR-520h expression, causing gefitinib to be pumped out of the cell.

Other information
Title:

New biomarker for lung cancer - focus on circSETD3.

Journal: J Biol Regul Homeost Agents
Published: 2021/3/27
PubMed ID: 33768996