circRNA basic information
circBase ID: -
Name: rno_circ_PVT1
Synonym: -
Host Gene: rno-miR-21-5p
 
 
 
Disease basic information
DO ID:
 10159
DO name: osteonecrosis
Disease details: steroid-induced osteonecrosis of the femoral head
Species: rat
Species details: rat
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Smad7/TGFbeta
Associated microRNA: rno-miR-21-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircPVT1 exerts protective effects against SIONFH via modulating miR-21-5p-mediated Smad7/TGFbeta pathway.
Other information
Title:

CircPVT1 up-regulation attenuates steroid-induced osteonecrosis of the femoral head through regulating miR-21-5p-mediated Smad7/TGFbeta signalling pathway.

Journal: J Cell Mol Med
Published: 2021/3/19
PubMed ID: 33733589