circRNA basic information
circBase ID: -
Name: hsa_circ_AFF2
Synonym: -
Host Gene: hsa-miR-6894-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BGC823, SGC7901, HGC27, MGC803
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ANTXR 1
Associated microRNA: hsa-miR-6894-5p
Biological function: The knockdown of circAFF2 dramatically suppressed the cell migration, invasion and proliferation of gastric cancer cells
Molecular mechanism: circAFF2 functioned as a sponge to absorb hsa-miR-6984-5p and elevated the expression of ANTXR 1
Survival: -
Supported No.:
 1
Description:

CircAFF2 acts as an oncogene in gastric cancer and exerts its effects via miR-6894-5p/ANTXR 1 signaling.
Other information
Title:

Circular RNA circAFF2 accelerates gastric cancer development by activating miR-6894-5p and regulating ANTXR 1 expression.

Journal: Clin Res Hepatol Gastroenterol
Published: 2021/3/17
PubMed ID: 33722777