circRNA basic information
circBase ID: -
Name: hsa_circ_MAP2K4
Synonym: -
Host Gene: hsa-miR-139-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Huh7, Hep3B, MHCC97H, HCCLM3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: YTHDF1
Associated microRNA: hsa-miR-139-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

hsa_circ_0007456(circMAP2K4) was validated to promote HCC cell proliferation by binding with hsa-miR-139-5p to promote YTHDF1 expression.
Other information
Title:

Analysis and Validation of circRNA-miRNA Network in Regulating m(6)A RNA Methylation Modulators Reveals CircMAP2K4/miR-139-5p/YTHDF1 Axis Involving the Proliferation of Hepatocellular Carcinoma.

Journal: Front Oncol
Published: 2021/3/13
PubMed ID: 33708621