circRNA basic information
circBase ID: hsa_circ_0000467
Name: -
Synonym: circ_0000467
Host Gene: hsa-miR-382-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW480, SW620, HT29, RKO, HCT116
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: EN2
Associated microRNA: hsa-miR-382-5p
Biological function: The depletion of circ_0000467 expression was found to impede the multiplication, migration, invasion, and epithelial-mesenchymal transition (EMT) processes in CRC cells,
Molecular mechanism: up-regulate EN2 expression via repressing hsa-miR-382-5p
Survival: -
Supported No.:
 4
Description:

circ_0000467 facilitates CRC development by modulating the miR-382-5p/EN2 axis, and circ_0000467 is a promising target for CRC therapy.
Other information
Title:

Circular RNA circ_0000467 regulates colorectal cancer development via miR-382-5p/EN2 axis.

Journal: Bioengineered
Published: 2021/3/10
PubMed ID: 33685351