circRNA basic information
circBase ID: -
Name: hsa_circ_NOTCH1
Synonym: -
Host Gene: hsa-miR-34c-5p
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SUNE1, SUNE2, 6-10B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: c-Myc
Associated microRNA: hsa-miR-34c-5p
Biological function: Circ-NOTCH1 knockdown suppressed NPC cell proliferation, invasion, and migration
Molecular mechanism: modulate c-Myc expression by sponging hsa-miR-34c-5p
Survival: -
Supported No.:
 1
Description:

c-Myc-induced circ-NOTCH1 promoted malignant phenotypes of NPC cells by regulating the miR-34c-5p/c-Myc axis.
Other information
Title:

c-Myc-induced circ-NOTCH1 promotes aggressive phenotypes of nasopharyngeal carcinoma cells by regulating the miR-34c-5p/c-Myc axis.

Journal: Cell Biol Int
Published: 2021/3/7
PubMed ID: 33675278