circRNA basic information
circBase ID: -
Name: hsa_circ_SOX4
Synonym: -
Host Gene: hsa-miR-432
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCCLM3, Huh6, SMMC-7721, QGY-7703
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-432
Biological function: Transfection of small interfering RNA against circSOX4 in HCC cells resulted in inhibited migration and proliferation of HCC cells, while an increase in cell apoptosis
Molecular mechanism: binding to microRNA-432
Survival: poor
Supported No.:
 1
Description:

CircSOX4, highly expressed in HCC, indicates a poor prognosis. CircSOX4 may mediate the progression of HCC by binding to microRNA-432.
Other information
Title:

Circular RNA circSOX4 promotes the proliferation, migration and apoptosis of hepatocellular carcinoma cells by down regulating microRNA-432 expression.

Journal: Eur Rev Med Pharmacol Sci
Published: 2021/3/5
PubMed ID: 33660794