circRNA basic information
circBase ID: -
Name: hsa_circ_RAD23B
Synonym: -
Host Gene: hsa-miR-1205
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW480 (CCL-228), SW620 (CCL-227)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TRIM44
Associated microRNA: hsa-miR-1205
Biological function: CRC cell proliferation, cell cycle progression, and cell metastasis were inhibited, while apoptosis was promoted by downregulating circRAD23B
Molecular mechanism: via the hsa-miR-1205/TRIM44 axis
Survival: -
Supported No.:
 4
Description:

the inhibition of circRAD23B retarded the progression of CRC via acting on the miR-1205/TRIM44 axis. CircRAD23B might be a novel target in CRC treatment.
Other information
Title:

Knockdown of circRAD23B Exerts Antitumor Response in Colorectal Cancer via the Regulation of miR-1205/TRIM44 axis.

Journal: Dig Dis Sci
Published: 2021/2/27
PubMed ID: 33634427