circRNA basic information
circBase ID: -
Name: hsa_circ_KIF2A
Synonym: -
Host Gene: hsa-miR-129-5p
 
 
 
Disease basic information
DO ID:
 769
DO name: neuroblastoma
Disease details: neuroblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SK-N-SH, SK-N-AS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PLK4
Associated microRNA: hsa-miR-129-5p
Biological function: CircKIF2A knockdown suppressed cell proliferation, migration, invasion and glycolysis
Molecular mechanism: positively modulate PLK4 expression via sponging hsa-miR-129-5p
Survival: -
Supported No.:
 2
Description:

circKIF2A knockdown hampered tumorigenesis in vivo. CircKIF2A knockdown suppressed cell proliferation, migration, invasion and glycolysis via downregulating PLK4 expression through miR-129-5p.
Other information
Title:

CircKIF2A contributes to cell proliferation, migration, invasion and glycolysis in human neuroblastoma by regulating miR-129-5p/PLK4 axis.

Journal: Mol Cell Biochem
Published: 2021/2/26
PubMed ID: 33630225