circRNA basic information
circBase ID: hsa_circ_0006174
Name: -
Synonym: circ_0006174
Host Gene: hsa-miR-138-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SW480, SW620, HT29, HCT116
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MACC1
Associated microRNA: hsa-miR-138-5p
Biological function: circ_0006174 knock down-mediated suppression on cell proliferation, migration and invasion, and promotion on cell apoptosis
Molecular mechanism: via sponging hsa-miR-138-5p to upregulate MACC1 expression
Survival: -
Supported No.:
 5
Description:

Circ_0006174 advanced CRC progression via sponging miR-138-5p to upregulate MACC1 expression, which may provide a promising molecular target for CRC treatment.
Other information
Title:

Circ_0006174 Accelerates Colorectal Cancer Progression Through Regulating miR-138-5p/MACC1 Axis.

Journal: Cancer Manag Res
Published: 2021/2/26
PubMed ID: 33628056