circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: hsa-miR-432-5p
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: PC-3, PANC1, ASPC1, CFPAC-1, MIApaCa-2, BXPC-3
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F3
Associated microRNA: hsa-miR-432-5p
Biological function: promoted the migration, invasion and proliferation of PC cells in vitro and tumor growth in vivo
Molecular mechanism: mediating E2F3 expression by sponging hsa-miR-432-5p
Survival: -
Supported No.:
 1
Description:

circCDR1as could promote the development of PC and might be a novel diagnostic target for PC.
Other information
Title:

Circular RNA CDR1as promotes tumor progression by regulating miR-432-5p/E2F3 axis in pancreatic cancer.

Journal: Cancer Cell Int
Published: 2021/2/18
PubMed ID: 33593338