circRNA basic information
circBase ID: hsa_circ_0123629
Name: hsa_circ_ARPP21
Synonym: -
Host Gene: hsa-miR-543
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: Huh7, Hep3B, HepG2, SMMC-7721, MHCC97H, HCCLM3
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: LIFR
Associated microRNA: hsa-miR-543
Biological function: suppresses the proliferation, invasion, and migration of hepatocellular carcinoma cells
Molecular mechanism: circARPP21/hsa-miR-543/LIFR axis
Survival: better
Supported No.:
 1
Description:

The circARPP21/miR-543/LIFR axis suppresses the proliferation, invasion, and migration of hepatocellular carcinoma cells. In addition, circARPP21 can serve as a biomarker in HCC, thus offering a potential new approach to HCC therapy.
Other information
Title:

Circular RNA circARPP21 Acts as a Sponge of miR-543 to Suppress Hepatocellular Carcinoma by Regulating LIFR.

Journal: Onco Targets Ther
Published: 2021/2/16
PubMed ID: 33584097