circRNA basic information
circBase ID: -
Name: hsa_circ_AASDH
Synonym: Circ-AASDH
Host Gene: hsa-miR-140-3p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A549, H1299, H524, H332, H1650
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F7
Associated microRNA: hsa-miR-140-3p
Biological function: silencing of circ-AASDH inhibited cell proliferation and migration
Molecular mechanism: regulating the expression of E2F7
Survival: -
Supported No.:
 1
Description:

Circ-AASDH/miR-140-3p/E2F7 regulating axis promoted the progression in LUAD. Our results provided ideas for understanding the biological mechanism of circ-AASDH and clarify potential therapeutic targets in LUAD.
Other information
Title:

Circ-AASDH functions as the progression of early stage lung adenocarcinoma by targeting miR-140-3p to activate E2F7 expression.

Journal: Transl Lung Cancer Res
Published: 2021/2/12
PubMed ID: 33569293