circRNA basic information
circBase ID: hsa_circ_0007534
Name: hsa_circ_DDX42
Synonym: -
Host Gene: hsa-miR-219a-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: hFOB1.19£¬143B£¬MG63£¬HOS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SOX5
Associated microRNA: hsa-miR-219a-5p
Biological function: Circ_0007534 knockdown repressed the proliferation, colony formation, migration, and invasion in OS cells
Molecular mechanism: targeted hsa-miR-219a-5p, and hsa-miR-219a-5p interacted with SOX5
Survival: -
Supported No.:
 2
Description:

circ_0007534 knockdown suppressed the growth of OS cells via regulating miR-219a-5p/SOX5 axis, providing a potential target for OS treatment and diagnosis.
Other information
Title:

Down-regulation of circular RNA hsa_circ_0007534 suppresses cell growth by regulating miR-219a-5p/SOX5 axis in osteosarcoma.

Journal: J Bone Oncol
Published: 2021/2/9
PubMed ID: 33552887