circRNA basic information
circBase ID: hsa_circ_0009172
Name: hsa_circ_DNA2
Synonym: -
Host Gene: hsa-miR-485-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: NTRK3
Associated microRNA: hsa-miR-485-3p
Biological function: inhibited proliferative, invasive and migrative potential of gastric cancer cells as well as epithelial-mesenchymal transition (EMT)-related proteins
Molecular mechanism: by sponging hsa-miR-485-3p to inhibit NTRK3
Survival: better
Supported No.:
 2
Description:

Functionally, hsa_circ_0009172 overexpression inhibited proliferative, invasive and migrative potential of gastric cancer cells as well as epithelial-mesenchymal transition (EMT)-related proteins by sponging miR-485-3p to inhibit NTRK3, while miR-485-3p overexpression could reverse the inhibitory effect of hsa_circ_0009172 on gastric cancer.
Other information
Title:

Circular RNA hsa_circ_0009172 suppresses gastric cancer by regulation of microRNA-485-3p-mediated NTRK3.

Journal: Cancer Gene Ther
Published: 2021/2/4
PubMed ID: 33531648