circRNA basic information
circBase ID: hsa_circ_0089153
Name: -
Synonym: circ_0089153
Host Gene: hsa-miR-608
 
 
 
Disease basic information
DO ID:
 0050894
DO name: ameloblastoma
Disease details: ameloblastoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human ameloblastoma cell line (AM-1)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: EGFR and p53
Associated microRNA: hsa-miR-608
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Six novel circRNAs were identified. Hsa_circ_0089153/hsa-miR-608 sponging was validated, hsa-miR-608 downregulated EGFR and p53, which might further regulate cell proliferation, differentiation, apoptosis, and cell cycle processes via the MAPK signaling pathway.
Other information
Title:

Identification of circ_0089153/miR-608/EGFR p53 axis in ameloblastoma via MAPK signaling pathway.

Journal: Oral Dis
Published: 2021/2/2
PubMed ID: 33523578