circRNA basic information
circBase ID: -
Name: hsa_circ_AKT3
Synonym: -
Host Gene: hsa-miR-17-5p
 
 
 
Disease basic information
DO ID:
 5041
DO name: esophageal cancer
Disease details: esophageal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: KYSE-150, TE-10, TE-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-17-5p
Biological function: proliferative, migratory, and invasive capacities of esophageal cancer cells were significantly enhanced by circAKT3 overexpression
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

CircAKT3 contributed to the malignant behaviors of esophageal cancer in vitro and in vivo by sponging miR-17-5p thus providing a potential target for treatment of esophageal cancer.
Other information
Title:

Circular RNA AKT3 governs malignant behaviors of esophageal cancer cells by sponging miR-17-5p.

Journal: World J Gastroenterol
Published: 2021/2/2
PubMed ID: 33519139