circRNA basic information
circBase ID: -
Name: hsa_circ_MTO1
Synonym: -
Host Gene: hsa-miR-630
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HOS, U2OS, Saos-2, MG63
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: KLF6
Associated microRNA: hsa-miR-630
Biological function: circMTO1 could inhibit cell proliferation, migration and invasion, and induced apoptosis
Molecular mechanism: serves as a sponge for hsa-miR-630 and KLF6 is a direct target of hsa-miR-630
Survival: -
Supported No.:
 2
Description:

circMTO1 could suppress osteosarcoma progression by regulating miR-630/KLF6 axis, which may highlight the diagnostic and therapeutic potential of these molecules in osteosarcoma treatment.
Other information
Title:

Circular RNA CircMTO1 suppressed proliferation and metastasis of osteosarcoma through miR-630/KLF6 axis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2021/1/29
PubMed ID: 33506896