circRNA basic information
circBase ID: -
Name: hsa_circ_FLNA
Synonym: -
Host Gene: hsa-miR-486-3p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal human bronchial epithelial cell line (BEAS2B), human lung cell lines (NCI-H520, SK-MES-1, H1299, A549, H23)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: XRCC1 and CYP1A1
Associated microRNA: hsa-miR-486-3p
Biological function: promote the proliferation, migration, and invasion
Molecular mechanism: regulating XRCC1 and CYP1A1
Survival: -
Supported No.:
 1
Description:

circFLNA acted as a sponge of miR-486-3p to promote the proliferation, migration, and invasion of lung cancer cells in vitro and in vivo by regulating XRCC1 and CYP1A1.
Other information
Title:

Circular RNA FLNA acts as a sponge of miR-486-3p in promoting lung cancer progression via regulating XRCC1 and CYP1A1.

Journal: Cancer Gene Ther
Published: 2021/1/28
PubMed ID: 33500536