circRNA basic information
circBase ID: -
Name: hsa_circ_PVT1
Synonym: -
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: ACHN, 786_O, Caki_1
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: TBX15
Associated microRNA: hsa-miR-145-5p
Biological function: circPVT1 promotes ccRCC growth and metastasis
Molecular mechanism: sponging hsa-miR-145-5p and regulating downstream target TBX15 expression
Survival: poor
Supported No.:
 1
Description:

circPVT1 promotes ccRCC growth and metastasis through sponging miR-145-5p and regulating downstream target TBX15 expression. The circPVT1/miR-145-5p/TBX15 axis might be a potential diagnostic marker and therapeutic target in ccRCC.
Other information
Title:

CircPVT1 promotes progression in clear cell renal cell carcinoma by sponging miR-145-5p and regulating TBX15 expression.

Journal: Cancer Sci
Published: 2021/1/17
PubMed ID: 33453148