circRNA basic information
circBase ID: -
Name: hsa_circ_TRPS1
Synonym: circ-TRPS1
Host Gene: hsa-miR-124-3p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PC3, LnCaP, DU145
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: EZH2
Associated microRNA: hsa-miR-124-3p
Biological function: promote metastasis and proliferation
Molecular mechanism: regulating hsa-miR-124-3p/EZH2 axis
Survival: poor
Supported No.:
 1
Description:

circ-TRPS1 suppressed PCa progression through functioning similar to a miR-124-3p sponge to enhance EZH2 expression and cancer stem-like cell differentiation.
Other information
Title:

Downregulation of circ-TRPS1 suppressed prostatic cancer prognoses by regulating miR-124-3p/EZH2 axis-mediated stemness.

Journal: Am J Cancer Res
Published: 2021/1/9
PubMed ID: 33415005