circRNA basic information
circBase ID: -
Name: hsa_circ_FOXM1
Synonym: -
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: H1581, A549
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ATG5
Associated microRNA: hsa-miR-149-5p
Biological function: Circ-FOXM1 knockdown suppressed NSCLC cell viability, migration, and autophagy, and induced cell apoptosis
Molecular mechanism: circ-FOXM1 targeted hsa-miR-149-5p to upregulate the ATG5 level
Survival: -
Supported No.:
 4
Description:

circ-FOXM1 knockdown attenuated the development of NSCLC through modulating the miR-149-5p/ATG5 axis, providing a theoretical basis for the therapy of NSCLC.
Other information
Title:

Circ-FOXM1 knockdown suppresses non-small cell lung cancer development by regulating the miR-149-5p/ATG5 axis.

Journal: Cell Cycle
Published: 2021/1/9
PubMed ID: 33413028