circRNA basic information
circBase ID: hsa_circ_0061395
Name: -
Synonym: circ_0061395
Host Gene: hsa-miR-877-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SNU-387, Huh-7
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PIK3R3
Associated microRNA: hsa-miR-877-5p
Biological function: Circ_0061395 silencing decreased tumor growth in vivo, and induced cell cycle arrest, apoptosis, repressed proliferation, invasion, and migration of HCC cells in vitro.
Molecular mechanism: via regulation of the hsa-miR-877-5p/PIK3R3 axis
Survival: -
Supported No.:
 4
Description:

Circ_0061395 facilitated HCC progression via regulating the miR-877-5p/PIK3R3 axis, providing a new perspective on the advancement of HCC.
Other information
Title:

Circular RNA hsa_circ_0061395 accelerates hepatocellular carcinoma progression via regulation of the miR-877-5p/PIK3R3 axis.

Journal: Cancer Cell Int
Published: 2021/1/8
PubMed ID: 33407443