circRNA basic information
circBase ID: -
Name: hsa_circ_PVT1
Synonym: -
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SKOV3, A2780
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: FOXM1
Associated microRNA: hsa-miR-149-5p
Biological function: Knockdown of circular PVT1 significantly suppressed OV cell proliferation, migration and invasion
Molecular mechanism: increased FOXM1 level via binding to hsa-miR-149-5p
Survival: poor
Supported No.:
 1
Description:

circular PVT1 increased FOXM1 level via binding to miR-149-5p and thus affected ovarian cancer cell viability and migration.
Other information
Title:

Circular PVT1 regulates cell proliferation and invasion via miR-149-5p/FOXM1 axis in ovarian cancer.

Journal: J Cancer
Published: 2021/1/5
PubMed ID: 33391456