circRNA basic information
circBase ID: -
Name: hsa_circ_PHIP
Synonym: -
Host Gene: hsa-miR-142-5p
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SCC9, SCC15, SCC25, CAL27
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: PHIP, ACTN4
Associated microRNA: hsa-miR-142-5p
Biological function: promote migration, invasion, and proliferation.
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circPHIP is overexpressed in OSCC and enhances its malignancy via an miR-142-5p/PHIP-ACTN4/AKT serine/threonine kinase 1 signaling axis.
Other information
Title:

circPHIP promotes oral squamous cell carcinoma progression by sponging miR-142-5p and regulating PHIP and ACTN4 expression.

Journal: Mol Ther Nucleic Acids
Published: 2020/12/31
PubMed ID: 33376626