circRNA basic information
circBase ID: -
Name: hsa_circ_ACAP2
Synonym: -
Host Gene: hsa-miR-21-5p
 
 
 
Disease basic information
DO ID:
 5520
DO name: head and neck squamous cell carcinoma
Disease details: head and neck squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HN-4, HN-9, HN-30, SCC-4, SCC-9, SCC-25, CAL-27
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: STAT3
Associated microRNA: hsa-miR-21-5p
Biological function: suppresses EMT and inhibits the proliferation and migration
Molecular mechanism: hsa-miR-21-5p/STAT3 signaling axis.
Survival: -
Supported No.:
 1
Description:

CircRNA_ACAP2 functions as a tumor suppressor gene in HNSCC and that its function is regulated via the miR-21-5p/STAT3 signaling axis.
Other information
Title:

CircRNA_ACAP2 Suppresses EMT in Head and Neck Squamous Cell Carcinoma by Targeting the miR-21-5p/STAT3 Signaling Axis.

Journal: Front Oncol
Published: 2020/12/29
PubMed ID: 33363013