circRNA basic information
circBase ID: hsa_circ_0004050
Name: hsa_circ_PKD2
Synonym: -
Host Gene: hsa-miR-1233-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1233-3p
Biological function: promote apoptosis and inhibit proliferation
Molecular mechanism: increase the protein expression of DUSP9 via targeting hsa-miR-1233-3p
Survival: better
Supported No.:
 1
Description:

hsa_circ_0004050 could markedly increase the protein expression of DUSP9 via targeting miR-1233-3p in A549 cells, thereby inhibiting the ERK/JNK signaling pathway.
Other information
Title:

HSA_CIRC_0004050 on proliferation and apoptosis of A549 cells through ERK/JNK signaling pathway.

Journal: J Biol Regul Homeost Agents
Published: 2020/12/23
PubMed ID: 33348975