circRNA basic information
circBase ID: hsa_circ_0000034
Name: -
Synonym: circ_0000034
Host Gene: hsa-miR-361-3p
 
 
 
Disease basic information
DO ID:
 768
DO name: retinoblastoma
Disease details: retinoblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Y79, WERI-Rb-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: STX17
Associated microRNA: hsa-miR-361-3p
Biological function: promote proliferation, migration, invasion, autophagy, and tumor growth, and inhibit apoptosis
Molecular mechanism: inhibiting hsa-miR-361-3p and upregulates STX17
Survival: -
Supported No.:
 3
Description:

circ_0000034 knockdown suppressed the development of RB by the modulation of miR-361-3p/STX17 axis.
Other information
Title:

Circular RNA circ_0000034 upregulates STX17 level to promote human retinoblastoma development via inhibiting miR-361-3p.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/12/19
PubMed ID: 33336726