circRNA basic information
circBase ID: -
Name: hsa_circ_HBEGF
Synonym: -
Host Gene: hsa-miR-646
 
 
 
Disease basic information
DO ID:
 1070
DO name: primary open angle glaucoma
Disease details: primary open-angle glaucoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: EGFR
Associated microRNA: hsa-miR-646
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circHBEGF could competitively bind to miR-646 as a miRNA sponge to regulate EGFR expression in HTMCs.
Other information
Title:

Oxidative Stress-Induced circHBEGF Promotes Extracellular Matrix Production via Regulating miR-646/EGFR in Human Trabecular Meshwork Cells.

Journal: Oxid Med Cell Longev
Published: 2020/12/19
PubMed ID: 33335643